About Isotretinoin
            
            Class: | Retinoid  
Use: | Treatment of severe acne (nodular acne) that has not responded to other therapies  
Adult dose: | 0.5 to 1 mg/kg/day, typically for 15 to 20 weeks; dosage may be adjusted based on response and tolerance  
Pediatric dose: | Not recommended for use in children under 12 years; for adolescents, dosing is similar to adults, based on weight  
Side effects: | Dry skin, chapped lips, dry eyes, nosebleeds, muscle aches, elevated liver enzymes, increased triglycerides  
Contrain
         
        
            
                
                
                
                
                    
                        Uses & Indications
                    
                    Treatment of severe acne (nodular acne) that has not responded to other therapies
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature (15-30°C or 59-86°F) in a tightly closed container, protected from light and moisture
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Douglas Pharmaceuticals Ltd, New Zealand
                    
                    
                    Package Size
                    30's (15's Blister x 2)
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 225.00
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        0.5 to 1 mg/kg/day, typically for 15 to 20 weeks; dosage may be adjusted based on response and tolerance
                    
                    
                        Pediatric Dose
                    
                    
                        Not recommended for use in children under 12 years; for adolescents, dosing is similar to adults, based on weight
                    
                 
                
                
                    
                        Side Effects
                    
                    Dry skin, chapped lips, dry eyes, nosebleeds, muscle aches, elevated liver enzymes, increased triglycerides
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Pregnancy (teratogenic), hypersensitivity to isotretinoin or any component of the formulation, liver disease, hypervitaminosis A
         
        
        
            
                Important Warnings
            
            Risk of severe birth defects if taken during pregnancy; requires enrollment in a risk management program (iPLEDGE); may cause mood changes, depression, or suicidal thoughts; monitor for signs of pancreatitis and liver dysfunction
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.