About Alectinib Hydrochloride
Class: | ALK inhibitor
Use: | Treatment of ALK-positive metastatic non-small cell lung cancer (NSCLC) in patients who have not received prior ALK inhibitor therapy or whose disease has progressed on crizotinib
Adult dose: | 600 mg orally twice daily or 450 mg orally once daily with food
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Fatigue, constipation, edema, myalgia, liver enzyme elevations, nausea, diarrhea, rash
Contraindications: | Hy
Uses & Indications
Treatment of ALK-positive metastatic non-small cell lung cancer (NSCLC) in patients who have not received prior ALK inhibitor therapy or whose disease has progressed on crizotinib
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F)
Manufacturer & Packaging
Manufacturer: F. Hoffmann-La Roche Ltd., SWITZERLAND
Package Size
224 (4 Packs x 56s) Capsules
Price & Supplier
Price in UAE: AED 29553.00
Dosage Information
Adult Dose
600 mg orally twice daily or 450 mg orally once daily with food
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Fatigue, constipation, edema, myalgia, liver enzyme elevations, nausea, diarrhea, rash
Contraindications & Precautions
Hypersensitivity to alectinib or any component of the formulation; severe hepatic impairment
Important Warnings
Risk of hepatotoxicity, interstitial lung disease/pneumonitis, bradycardia, and embryo-fetal toxicity; monitor liver function tests and pulmonary symptoms during treatment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.