About Amivantamab
Class: | Monoclonal antibody (EGFR and MET inhibitor)
Use: | Treatment of adult patients with non-small cell lung cancer (NSCLC) that is positive for epidermal growth factor receptor (EGFR) exon 20 insertion mutations
Adult dose: | Initial dose of 1050 mg administered as an intravenous infusion over 60 minutes, followed by 1400 mg once weekly for subsequent doses
Pediatric dose: | Safety and efficacy have not been established in pediatric patients; not recommended for use in this populatio
Drug Class
Monoclonal antibody (EGFR and MET inhibitor)
Uses & Indications
Treatment of adult patients with non-small cell lung cancer (NSCLC) that is positive for epidermal growth factor receptor (EGFR) exon 20 insertion mutations
Storage Requirements
Store refrigerated at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; may be stored at room temperature (up to 25°C or 77°F) for up to 24 hours prior to administration
Manufacturer & Packaging
Manufacturer: Janssen-Cilag AG, SWITZERLAND
Package Size
1's
Price & Supplier
Price in UAE: AED 5668.15
Dosage Information
Adult Dose
Initial dose of 1050 mg administered as an intravenous infusion over 60 minutes, followed by 1400 mg once weekly for subsequent doses
Pediatric Dose
Safety and efficacy have not been established in pediatric patients; not recommended for use in this population
Side Effects
Common side effects include infusion-related reactions, rash, diarrhea, nausea, fatigue, and decreased appetite
Contraindications & Precautions
Hypersensitivity to amivantamab or any component of the formulation; caution in patients with a history of interstitial lung disease or pneumonitis
Important Warnings
Risk of severe infusion-related reactions; monitor patients during and after infusion; potential for interstitial lung disease; consider benefits and risks before use in patients with a history of lung disease
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.