About Anifrolumab
Class: | Monoclonal antibody (IgG1κ)
Use: | Treatment of moderate to severe systemic lupus erythematosus (SLE) in adults
Adult dose: | 300 mg administered as an intravenous infusion every 4 weeks after an initial loading dose of 300 mg at weeks 0, 2, and 4
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in individuals under 18 years of age
Side effects: | Common side effects include upper respiratory infections, headache, infusion-rela
Drug Class
Monoclonal antibody (IgG1κ)
Uses & Indications
Treatment of moderate to severe systemic lupus erythematosus (SLE) in adults
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; may be stored at room temperature (up to 25°C or 77°F) for a maximum of 48 hours prior to use
Manufacturer & Packaging
Manufacturer: AstraZeneca AB. [Sodertalje;Sweden], Sweden
Package Size
1 Glass Vial
Price & Supplier
Price in UAE: AED 5128.50
Dosage Information
Adult Dose
300 mg administered as an intravenous infusion every 4 weeks after an initial loading dose of 300 mg at weeks 0, 2, and 4
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in individuals under 18 years of age
Side Effects
Common side effects include upper respiratory infections, headache, infusion-related reactions, nausea, and fatigue
Contraindications & Precautions
Hypersensitivity to anifrolumab or any component of the formulation; active infections (e.g., tuberculosis) should be treated prior to initiation
Important Warnings
Risk of serious infections; monitor for signs of infection; may cause hypersensitivity reactions; caution in patients with a history of malignancy; not recommended for use in patients with severe hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.