About Aprotinin
Class: | Antifibrinolytic agent
Use: | Aprotinin is used to reduce blood loss and the need for blood transfusions during surgical procedures, particularly in cardiac surgery and high-risk orthopedic surgeries.
Adult dose: | The typical adult dosing for aprotinin is 100,000 U administered as a loading dose prior to surgery, followed by an infusion of 5,000 U/hour during surgery.
Pediatric dose: | The safety and efficacy of aprotinin in pediatric patients have not been established; therefore
Drug Class
Antifibrinolytic agent
Uses & Indications
Aprotinin is used to reduce blood loss and the need for blood transfusions during surgical procedures, particularly in cardiac surgery and high-risk orthopedic surgeries.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) and protect from light. Do not freeze.
Manufacturer & Packaging
Manufacturer: Bayer Healthcare AG, GERMANY
Package Size
1 Vial x 10ml
Price & Supplier
Price in UAE: AED 133.13
Dosage Information
Adult Dose
The typical adult dosing for aprotinin is 100,000 U administered as a loading dose prior to surgery, followed by an infusion of 5,000 U/hour during surgery.
Pediatric Dose
The safety and efficacy of aprotinin in pediatric patients have not been established; therefore, it is not routinely recommended for use in this population.
Side Effects
Common side effects include hypotension, nausea, vomiting, diarrhea, and allergic reactions. Serious side effects may include renal impairment and thromboembolic events.
Contraindications & Precautions
Aprotinin is contraindicated in patients with a history of hypersensitivity to aprotinin or any of its components, patients with active bleeding disorders, and those with severe renal impairment.
Important Warnings
Aprotinin has been associated with an increased risk of renal failure and thromboembolic events. It should be used with caution in patients with pre-existing renal impairment or those at risk for thromboembolic complications.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.