About Asparaginase (L-Asparaginase) (ERWINASE)
Class: | Enzyme, Antineoplastic
Use: | Treatment of acute lymphoblastic leukemia (ALL) in patients who are hypersensitive to E. coli-derived asparaginase or have developed a hypersensitivity reaction to other forms of asparaginase.
Adult dose: | 10,000 units/m² administered intramuscularly or intravenously once every 14 days.
Pediatric dose: | 10,000 units/m² administered intramuscularly or intravenously once every 14 days.
Side effects: | Common side effects include hypersensitivity rea
Drug Class
Enzyme, Antineoplastic
Uses & Indications
Treatment of acute lymphoblastic leukemia (ALL) in patients who are hypersensitive to E. coli-derived asparaginase or have developed a hypersensitivity reaction to other forms of asparaginase.
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Manufacturer & Packaging
Manufacturer: Porton Biopharma Limited, United Kingdom
Package Size
Vial x 5's
Price & Supplier
Price in UAE: AED 22617.50
Dosage Information
Adult Dose
10,000 units/m² administered intramuscularly or intravenously once every 14 days.
Pediatric Dose
10,000 units/m² administered intramuscularly or intravenously once every 14 days.
Side Effects
Common side effects include hypersensitivity reactions, pancreatitis, hepatotoxicity, thrombosis, and central nervous system effects (e.g., confusion, seizures).
Contraindications & Precautions
Hypersensitivity to asparaginase or any component of the formulation; history of pancreatitis; severe liver dysfunction; active bleeding disorders.
Important Warnings
Risk of serious hypersensitivity reactions; monitor for signs of pancreatitis; may cause coagulopathy; caution in patients with liver impairment; monitor blood glucose levels due to potential for hyperglycemia.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.