About Aztreonam,Avibactam Sodium 542 mg equivalent to Avibactam Moiety 500mg
Class: | Monobactam antibiotic combined with a beta-lactamase inhibitor
Use: | Treatment of infections caused by Gram-negative bacteria, including complicated urinary tract infections and intra-abdominal infections; used in combination with other antibiotics to enhance efficacy against resistant organisms.
Adult dose: | Aztreonam 1 g every 8 hours IV; Avibactam Sodium 500 mg IV every 8 hours, typically administered over 30 minutes.
Pediatric dose: | Aztreonam 30 mg/kg every 8 hours IV (max
Drug Class
Monobactam antibiotic combined with a beta-lactamase inhibitor
Uses & Indications
Treatment of infections caused by Gram-negative bacteria, including complicated urinary tract infections and intra-abdominal infections; used in combination with other antibiotics to enhance efficacy against resistant organisms.
Storage Requirements
Store at 20-25°C (68-77°F); protect from light; reconstituted solutions should be used immediately or stored at 2-8°C (36-46°F) for up to 24 hours.
Manufacturer & Packaging
Manufacturer: Pfizer Europe MA EEIG [Bruxells;BELGIUM], Belgium
Package Size
10 Glass Vials
Price & Supplier
Price in UAE: AED 9165.50
Dosage Information
Adult Dose
Aztreonam 1 g every 8 hours IV; Avibactam Sodium 500 mg IV every 8 hours, typically administered over 30 minutes.
Pediatric Dose
Aztreonam 30 mg/kg every 8 hours IV (maximum 2 g/dose); Avibactam Sodium dosing in pediatric patients is based on clinical judgment and specific infection type.
Side Effects
Common side effects include nausea, vomiting, diarrhea, headache, and rash. Serious side effects may include allergic reactions, liver enzyme elevations, and Clostridium difficile-associated diarrhea.
Contraindications & Precautions
Known hypersensitivity to aztreonam, avibactam, or any component of the formulation; caution in patients with a history of severe allergic reactions to beta-lactam antibiotics.
Important Warnings
Use with caution in patients with renal impairment; monitor renal function; potential for superinfection with prolonged use; may cause false-positive results for urinary glucose tests.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.