About bempedoic acid,Ezetimibe
Class: | Bempedoic acid: ATP-citrate lyase inhibitor; Ezetimibe: Cholesterol absorption inhibitor
Use: | Bempedoic acid is used as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease. Ezetimibe is used to lower cholesterol levels in patients with primary hyperlipidemia or mixed dyslipidemia, either alone or in combination with statins.
Adult dose: | Bempedoic acid: 180
Drug Class
Bempedoic acid: ATP-citrate lyase inhibitor; Ezetimibe: Cholesterol absorption inhibitor
Uses & Indications
Bempedoic acid is used as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease. Ezetimibe is used to lower cholesterol levels in patients with primary hyperlipidemia or mixed dyslipidemia, either alone or in combination with statins.
Storage Requirements
Store at room temperature, away from moisture and heat. Keep out of reach of children.
Manufacturer & Packaging
Manufacturer: Daiichi Sankyo Europe GmbH, GERMANY
Package Size
28's
Price & Supplier
Price in UAE: AED 381.96
Dosage Information
Adult Dose
Bempedoic acid: 180 mg orally once daily; Ezetimibe: 10 mg orally once daily.
Pediatric Dose
Not established for bempedoic acid; Ezetimibe is not recommended for use in pediatric patients under 10 years of age.
Side Effects
Common side effects of bempedoic acid include muscle spasms, abdominal pain, and elevated liver enzymes. Ezetimibe may cause diarrhea, fatigue, and abdominal pain.
Contraindications & Precautions
Bempedoic acid is contraindicated in patients with a history of hypersensitivity to the drug or its components. Ezetimibe is contraindicated in patients with active liver disease or unexplained persistent elevations in hepatic transaminases.
Important Warnings
Bempedoic acid may increase the risk of tendon rupture and should be used with caution in patients with a history of tendon disorders. Ezetimibe should be used with caution in patients with liver impairment. Both medications should be monitored for potential interactions with other lipid-lowering therapies.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.