About Bevacizumab(ZIRABEV)
            
            Class: | Monoclonal antibody (VEGF inhibitor)  
Use: | Treatment of various cancers including metastatic colorectal cancer, non-squamous non-small cell lung cancer, glioblastoma, renal cell carcinoma, and cervical cancer  
Adult dose: | 5 mg/kg IV every 2 weeks or 10 mg/kg IV every 3 weeks, depending on the specific cancer being treated  
Pediatric dose: | Safety and efficacy not established in pediatric patients; use is not recommended  
Side effects: | Hypertension, fatigue, headache, gastroin
         
        
            
                
                
                    
                        Drug Class
                    
                    Monoclonal antibody (VEGF inhibitor)
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of various cancers including metastatic colorectal cancer, non-squamous non-small cell lung cancer, glioblastoma, renal cell carcinoma, and cervical cancer
                 
                
                
                    
                        Storage Requirements
                    
                    Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: PFIZER EUROPE MA EEIG, BELGIUM
                    
                    
                    Package Size
                    16ml Glass Vial
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 5569.00
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        5 mg/kg IV every 2 weeks or 10 mg/kg IV every 3 weeks, depending on the specific cancer being treated
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in pediatric patients; use is not recommended
                    
                 
                
                
                    
                        Side Effects
                    
                    Hypertension, fatigue, headache, gastrointestinal perforations, proteinuria, bleeding complications, wound healing complications
                 
             
         
        
        
            
                Contraindications & Precautions
            
            History of hypersensitivity to bevacizumab or any component of the formulation; recent surgery or wound healing complications; severe hemorrhage
         
        
        
            
                Important Warnings
            
            Risk of serious adverse reactions including gastrointestinal perforations, severe bleeding, and arterial thromboembolic events; monitor blood pressure regularly; caution in patients with a history of thromboembolic events or recent surgery
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.