About Bortezomib (as a mannitol boronic ester)
Class: | Proteasome inhibitor
Use: | Treatment of multiple myeloma and certain types of lymphoma
Adult dose: | 1.3 mg/m² IV on days 1, 4, 8, and 11 of a 21-day cycle, may be adjusted based on tolerance
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Nausea, diarrhea, fatigue, peripheral neuropathy, thrombocytopenia, neutropenia
Contraindications: | Hypersensitivity to bortezomib or any component of the formulation; caution in patients with ac
Drug Class
Proteasome inhibitor
Uses & Indications
Treatment of multiple myeloma and certain types of lymphoma
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: Pharmascience Inc., CANADA
Package Size
1 glass vial
Price & Supplier
Price in UAE: AED 2447.50
Dosage Information
Adult Dose
1.3 mg/m² IV on days 1, 4, 8, and 11 of a 21-day cycle, may be adjusted based on tolerance
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Nausea, diarrhea, fatigue, peripheral neuropathy, thrombocytopenia, neutropenia
Contraindications & Precautions
Hypersensitivity to bortezomib or any component of the formulation; caution in patients with active infections or severe hepatic impairment
Important Warnings
Risk of progressive multifocal leukoencephalopathy (PML), serious infections, and cardiac events; monitor blood counts regularly; may cause fetal harm if administered during pregnancy.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.