About Bosentan Monohydrate
Class: | Endothelin receptor antagonist
Use: | Treatment of pulmonary arterial hypertension (PAH) to improve exercise ability and delay clinical worsening
Adult dose: | Initial dose of 62.5 mg twice daily for 4 weeks, then increase to 125 mg twice daily
Pediatric dose: | Not established; use in pediatric patients should be determined by a healthcare provider
Side effects: | Headache, flushing, hypotension, liver enzyme elevations, peripheral edema, nasal congestion
Contraindications: |
Drug Class
Endothelin receptor antagonist
Uses & Indications
Treatment of pulmonary arterial hypertension (PAH) to improve exercise ability and delay clinical worsening
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Serketi, TURKEY
Package Size
56‘s
Price & Supplier
Price in UAE: AED 8654.50
Dosage Information
Adult Dose
Initial dose of 62.5 mg twice daily for 4 weeks, then increase to 125 mg twice daily
Pediatric Dose
Not established; use in pediatric patients should be determined by a healthcare provider
Side Effects
Headache, flushing, hypotension, liver enzyme elevations, peripheral edema, nasal congestion
Contraindications & Precautions
Hypersensitivity to bosentan or any component of the formulation; concurrent use with glyburide, cyclosporine A, or other strong CYP2C9 inhibitors; pregnancy (category X)
Important Warnings
Risk of hepatotoxicity; monitor liver function tests before and during treatment; may cause fetal harm; use effective contraception in females of childbearing potential
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.