About Burosumab
Class: | Monoclonal antibody (anti-FGF23)
Use: | Treatment of X-linked hypophosphatemia (XLH) in adults and children aged 1 year and older
Adult dose: | 1 mg/kg administered subcutaneously every 2 weeks; may be adjusted based on serum phosphorus levels
Pediatric dose: | 0.8 mg/kg to 1 mg/kg administered subcutaneously every 2 weeks; dosing may vary based on age and weight
Side effects: | Injection site reactions, headache, nausea, fatigue, and elevated serum phosphate levels
Contraindi
Drug Class
Monoclonal antibody (anti-FGF23)
Uses & Indications
Treatment of X-linked hypophosphatemia (XLH) in adults and children aged 1 year and older
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; may be stored at room temperature for up to 7 days prior to use
Manufacturer & Packaging
Manufacturer: Kyowa Kirin Inc., U.S.A
Package Size
Vial
Price & Supplier
Price in UAE: AED 16139.00
Dosage Information
Adult Dose
1 mg/kg administered subcutaneously every 2 weeks; may be adjusted based on serum phosphorus levels
Pediatric Dose
0.8 mg/kg to 1 mg/kg administered subcutaneously every 2 weeks; dosing may vary based on age and weight
Side Effects
Injection site reactions, headache, nausea, fatigue, and elevated serum phosphate levels
Contraindications & Precautions
Hypersensitivity to burosumab or any component of the formulation; caution in patients with severe renal impairment
Important Warnings
Risk of hypophosphatemia; monitor serum phosphorus levels regularly; potential for osteosarcoma in patients with XLH; not recommended for use in patients with severe renal impairment or end-stage renal disease
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.