About C1 Esterase Inhibitor (Human)
Class: | C1 Esterase Inhibitor (Human)
Use: | Treatment and prevention of angioedema attacks in patients with hereditary angioedema (HAE)
Adult dose: | 1000 IU (1 vial) administered intravenously every 3 to 4 days for prophylaxis; for acute attacks, 500 IU to 1000 IU may be administered as needed
Pediatric dose: | Safety and efficacy not established in children under 12 years; dosing in adolescents may be similar to adults, but should be determined by a healthcare provider
Side effects:
Drug Class
C1 Esterase Inhibitor (Human)
Uses & Indications
Treatment and prevention of angioedema attacks in patients with hereditary angioedema (HAE)
Storage Requirements
Store lyophilized powder at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; reconstituted solution should be used immediately or stored at 2°C to 8°C for up to 24 hours
Manufacturer & Packaging
Manufacturer: Shire ViroPharma Inc, U.S.A
Package Size
Vacuum-Sealed Single-Use Glass Vial
Price & Supplier
Price in UAE: AED 3297.05
Dosage Information
Adult Dose
1000 IU (1 vial) administered intravenously every 3 to 4 days for prophylaxis; for acute attacks, 500 IU to 1000 IU may be administered as needed
Pediatric Dose
Safety and efficacy not established in children under 12 years; dosing in adolescents may be similar to adults, but should be determined by a healthcare provider
Side Effects
Headache, nausea, abdominal pain, diarrhea, rash, and infusion site reactions
Contraindications & Precautions
Known hypersensitivity to C1 esterase inhibitor products or any component of the formulation; history of severe allergic reactions
Important Warnings
Risk of thromboembolic events; monitor for signs of allergic reactions; not for intramuscular or subcutaneous use; should not be used in patients with a history of severe allergic reactions to C1 esterase inhibitors
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.