About Canakinumab
Class: | Monoclonal antibody (IL-1β inhibitor)
Use: | Treatment of systemic juvenile idiopathic arthritis (sJIA), adult-onset Still's disease (AOSD), and other inflammatory conditions such as chronic inflammatory diseases
Adult dose: | 150 mg subcutaneously every 4 weeks; may be adjusted based on clinical response
Pediatric dose: | For children ≥2 years with sJIA: 4 mg/kg subcutaneously every 4 weeks; may be increased to 8 mg/kg if inadequate response
Side effects: | Injection site react
Drug Class
Monoclonal antibody (IL-1β inhibitor)
Uses & Indications
Treatment of systemic juvenile idiopathic arthritis (sJIA), adult-onset Still's disease (AOSD), and other inflammatory conditions such as chronic inflammatory diseases
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: Novartis Pharma AG, SWITZERLAND
Package Size
1 Glass Vial (Powder)
Price & Supplier
Price in UAE: AED 73212.50
Dosage Information
Adult Dose
150 mg subcutaneously every 4 weeks; may be adjusted based on clinical response
Pediatric Dose
For children ≥2 years with sJIA: 4 mg/kg subcutaneously every 4 weeks; may be increased to 8 mg/kg if inadequate response
Side Effects
Injection site reactions, increased risk of infections, headache, nausea, diarrhea, abdominal pain
Contraindications & Precautions
Active infections, hypersensitivity to canakinumab or any component of the formulation, live vaccines during treatment
Important Warnings
Risk of serious infections, including tuberculosis; monitor for signs of infection; may cause hypersensitivity reactions; not recommended for use in patients with active or chronic infections
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.