About capivasertib
Class: | AKT inhibitor
Use: | Capivasertib is used in combination with other medications for the treatment of certain types of breast cancer, specifically hormone receptor-positive, HER2-negative advanced or metastatic breast cancer in patients with mutations in the PIK3CA, AKT1, or PTEN genes.
Adult dose: | The standard adult dosing for capivasertib is 400 mg (two 200 mg tablets) taken orally twice daily on an intermittent dosing schedule of 4 days on treatment followed by 3 days off treatment,
Uses & Indications
Capivasertib is used in combination with other medications for the treatment of certain types of breast cancer, specifically hormone receptor-positive, HER2-negative advanced or metastatic breast cancer in patients with mutations in the PIK3CA, AKT1, or PTEN genes.
Storage Requirements
Store at room temperature, between 20°C to 25°C (68°F to 77°F), in the original package to protect from moisture.
Manufacturer & Packaging
Manufacturer: ASTRAZENICA PHARMACEUTICAL LP, United States of America
Package Size
64's
Price & Supplier
Price in UAE: AED 105040.00
Dosage Information
Adult Dose
The standard adult dosing for capivasertib is 400 mg (two 200 mg tablets) taken orally twice daily on an intermittent dosing schedule of 4 days on treatment followed by 3 days off treatment, in combination with other prescribed cancer therapies.
Pediatric Dose
Not applicable; capivasertib is not approved for use in pediatric patients.
Side Effects
Common side effects include diarrhea, nausea, vomiting, decreased appetite, rash, fatigue, and elevated liver enzymes. Patients may also experience hyperglycemia and hypertension.
Contraindications & Precautions
Contraindications include hypersensitivity to capivasertib or any of its excipients. Caution is advised in patients with severe hepatic impairment.
Important Warnings
Important safety warnings include the risk of severe diarrhea, hyperglycemia, and skin reactions. Regular monitoring of blood glucose levels and liver function tests is recommended. Use with caution in patients with a history of cardiovascular disease.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.