About Caplacizumab
Class: | Monoclonal antibody (anti-von Willebrand factor)
Use: | Treatment of acquired thrombotic thrombocytopenic purpura (aTTP) in adults
Adult dose: | Initial dose: 10 mg IV bolus once daily for 30 minutes, followed by 10 mg SC once daily until platelet count recovery (typically 30 days)
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in children
Side effects: | Bleeding events, headache, nausea, fatigue, infusion-related reactions
Drug Class
Monoclonal antibody (anti-von Willebrand factor)
Uses & Indications
Treatment of acquired thrombotic thrombocytopenic purpura (aTTP) in adults
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: Ablynx NV, Belgium
Package Size
1 Vial
Price & Supplier
Price in UAE: AED 20997.00
Dosage Information
Adult Dose
Initial dose: 10 mg IV bolus once daily for 30 minutes, followed by 10 mg SC once daily until platelet count recovery (typically 30 days)
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children
Side Effects
Bleeding events, headache, nausea, fatigue, infusion-related reactions
Contraindications & Precautions
Hypersensitivity to caplacizumab or any component of the formulation; active bleeding disorders
Important Warnings
Risk of bleeding; monitor for signs of bleeding; discontinue if severe bleeding occurs; use caution in patients with a history of bleeding disorders or those on anticoagulant therapy
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.