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Ceftolozane Sulfate,Tazobactam Sodium – Uses, Dosage, and Brands in UAE

Brand Name: ZERBAXA
Strength: 1147 mg,537 mg | Form: Powder For Solution For Intavenous Infusion
Price in UAE: AED 4838.50
Available in UAE pharmacies

About Ceftolozane Sulfate,Tazobactam Sodium

Class: | Antibiotic (cephalosporin and beta-lactamase inhibitor combination) Use: | Treatment of complicated urinary tract infections (cUTIs) and complicated intra-abdominal infections (cIAIs) caused by susceptible Gram-negative and Gram-positive bacteria Adult dose: | 3 g (2 g ceftolozane and 1 g tazobactam) administered intravenously every 8 hours for 4 to 14 days, depending on the severity of the infection Pediatric dose: | Not established for pediatric patients; safety and efficacy hav

Drug Class

Antibiotic (cephalosporin and beta-lactamase inhibitor combination)

Uses & Indications

Treatment of complicated urinary tract infections (cUTIs) and complicated intra-abdominal infections (cIAIs) caused by susceptible Gram-negative and Gram-positive bacteria

Storage Requirements

Store at 20°C to 25°C (68°F to 77°F); protect from light; reconstituted solution should be used immediately or stored at 2°C to 8°C (36°F to 46°F) for up to 24 hours

Manufacturer & Packaging

Manufacturer: Merck Canada Inc., CANADA

Package Size

10 Vials

Price & Supplier

Price in UAE: AED 4838.50

Dosage Information

Adult Dose

3 g (2 g ceftolozane and 1 g tazobactam) administered intravenously every 8 hours for 4 to 14 days, depending on the severity of the infection

Pediatric Dose

Not established for pediatric patients; safety and efficacy have not been determined in patients under 18 years of age

Side Effects

Common side effects include nausea, diarrhea, headache, and infusion site reactions; serious side effects may include hypersensitivity reactions, Clostridium difficile-associated diarrhea, and renal impairment

Contraindications & Precautions

Known hypersensitivity to ceftolozane, tazobactam, or any component of the formulation; caution in patients with a history of severe allergic reactions to penicillins or other beta-lactam antibiotics

Important Warnings

Use with caution in patients with renal impairment; monitor renal function during therapy; potential for superinfection with prolonged use; may cause false-positive results for urine glucose tests

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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