About Chlorambucil
Class: | Alkylating agent
Use: | Treatment of chronic lymphocytic leukemia (CLL), Hodgkin's lymphoma, and non-Hodgkin's lymphoma; also used off-label for other malignancies and certain autoimmune disorders.
Adult dose: | Initial dose is typically 0.1 to 0.2 mg/kg/day, with adjustments based on response and tolerance; maintenance doses may vary.
Pediatric dose: | Not established; use in pediatric patients should be based on clinical judgment and careful monitoring.
Side effects: | Common
Drug Class
Alkylating agent
Uses & Indications
Treatment of chronic lymphocytic leukemia (CLL), Hodgkin's lymphoma, and non-Hodgkin's lymphoma; also used off-label for other malignancies and certain autoimmune disorders.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from light and moisture.
Manufacturer & Packaging
Manufacturer: Excella GmbH, GERMANY
Package Size
25's Bottle
Price & Supplier
Price in UAE: AED 45.40
Dosage Information
Adult Dose
Initial dose is typically 0.1 to 0.2 mg/kg/day, with adjustments based on response and tolerance; maintenance doses may vary.
Pediatric Dose
Not established; use in pediatric patients should be based on clinical judgment and careful monitoring.
Side Effects
Common side effects include myelosuppression (bone marrow suppression), nausea, vomiting, diarrhea, stomatitis, and alopecia.
Contraindications & Precautions
Hypersensitivity to chlorambucil or any component of the formulation; severe bone marrow suppression; active infections; pregnancy and breastfeeding.
Important Warnings
Risk of secondary malignancies; monitor blood counts regularly; may cause severe allergic reactions; caution in patients with liver or kidney impairment; avoid vaccination with live vaccines during treatment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.