About Darbepoetin alfa
Class: | Erythropoiesis-stimulating agent (ESA)
Use: | Treatment of anemia due to chronic kidney disease (CKD), anemia in cancer patients receiving chemotherapy, and anemia in patients with HIV receiving zidovudine.
Adult dose: | For CKD: 0.45 mcg/kg once every 4 weeks; for chemotherapy-induced anemia: 2.25 mcg/kg once every 3 weeks or 500 mcg once every 3 weeks; for HIV-related anemia: 40 mcg once weekly.
Pediatric dose: | For CKD: 0.45 mcg/kg once every 4 weeks; dosing should be individu
Drug Class
Erythropoiesis-stimulating agent (ESA)
Uses & Indications
Treatment of anemia due to chronic kidney disease (CKD), anemia in cancer patients receiving chemotherapy, and anemia in patients with HIV receiving zidovudine.
Storage Requirements
Store in the refrigerator (2°C to 8°C). Do not freeze. Protect from light.
Manufacturer & Packaging
Manufacturer: AMGEN EUROPE B.V. [BREDA-Netherlands], Netherlands
Package Size
0.4ml Pre-filled Syringe x 4
Price & Supplier
Price in UAE: AED 2364.00
Dosage Information
Adult Dose
For CKD: 0.45 mcg/kg once every 4 weeks; for chemotherapy-induced anemia: 2.25 mcg/kg once every 3 weeks or 500 mcg once every 3 weeks; for HIV-related anemia: 40 mcg once weekly.
Pediatric Dose
For CKD: 0.45 mcg/kg once every 4 weeks; dosing should be individualized based on hemoglobin levels.
Side Effects
Hypertension, headache, fatigue, nausea, diarrhea, edema, and injection site reactions.
Contraindications & Precautions
Uncontrolled hypertension, pure red cell aplasia (PRCA) following erythropoietin therapy, and hypersensitivity to darbepoetin alfa or any component of the formulation.
Important Warnings
Risk of serious cardiovascular events, including stroke and myocardial infarction, especially in patients with pre-existing cardiovascular conditions; monitor hemoglobin levels to avoid excessive elevation.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.