About Daunorubicin,Cytarabine
Class: | Antineoplastic agent, Combination chemotherapy (liposomal formulation)
Use: | Treatment of adults with newly diagnosed acute myeloid leukemia (AML) and secondary AML
Adult dose: | Recommended dose is 44 mg/m² daunorubicin and 100 mg/m² cytarabine administered as a continuous intravenous infusion over 90 minutes on days 1, 3, and 5 of a 28-day cycle
Pediatric dose: | Safety and efficacy in pediatric patients have not been established; use is not recommended
Side effects: | Common
Drug Class
Antineoplastic agent, Combination chemotherapy (liposomal formulation)
Uses & Indications
Treatment of adults with newly diagnosed acute myeloid leukemia (AML) and secondary AML
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once reconstituted, use immediately or store at 2°C to 8°C for up to 24 hours
Manufacturer & Packaging
Manufacturer: JAZZ Pharmaceutical Ireland Limited , Ireland
Package Size
1's
Price & Supplier
Price in UAE: AED 25547.10
Dosage Information
Adult Dose
Recommended dose is 44 mg/m² daunorubicin and 100 mg/m² cytarabine administered as a continuous intravenous infusion over 90 minutes on days 1, 3, and 5 of a 28-day cycle
Pediatric Dose
Safety and efficacy in pediatric patients have not been established; use is not recommended
Side Effects
Common side effects include nausea, vomiting, fever, fatigue, low blood cell counts (neutropenia, thrombocytopenia, anemia), and infusion-related reactions
Contraindications & Precautions
Hypersensitivity to daunorubicin, cytarabine, or any component of the formulation; patients with severe hepatic impairment; active infections; pregnancy and breastfeeding
Important Warnings
Risk of serious adverse reactions including severe myelosuppression, infections, cardiotoxicity, and infusion-related reactions; monitor blood counts and cardiac function; avoid use in patients with a history of congestive heart failure or significant arrhythmias
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.