Defibrotide (DEFITELIO) – Uses, Dosage & Brands in UAE

About Defibrotide

Class: | Antithrombotic agent, specifically a deoxyribonucleic acid (DNA) derivative Use: | Treatment of hepatic veno-occlusive disease (VOD) in patients undergoing hematopoietic stem cell transplantation Adult dose: | 25 mg/kg IV every 6 hours for 21 days Pediatric dose: | 25 mg/kg IV every 6 hours for 21 days (same as adults) Side effects: | Hypotension, fever, nausea, vomiting, diarrhea, headache, and bleeding Contraindications: | Hypersensitivity to defibrotide or any component of

Drug Class

Antithrombotic agent, specifically a deoxyribonucleic acid (DNA) derivative

Uses & Indications

Treatment of hepatic veno-occlusive disease (VOD) in patients undergoing hematopoietic stem cell transplantation

Storage Requirements

Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light

Manufacturer & Packaging

Manufacturer: Gentium Srl, Italy

Package Size

2.5ml Vials x 10's

Price & Supplier

Price in UAE: AED 23340.80

Dosage Information

Adult Dose

25 mg/kg IV every 6 hours for 21 days

Pediatric Dose

25 mg/kg IV every 6 hours for 21 days (same as adults)

Side Effects

Hypotension, fever, nausea, vomiting, diarrhea, headache, and bleeding

Important Warnings

Risk of bleeding; monitor for signs of bleeding; use with caution in patients with renal impairment; not recommended for use in patients with severe hepatic impairment

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Defibrotide – Uses, Dosage, and Brands in UAE