About Donanemab
Class: | Monoclonal antibody (anti-amyloid beta)
Use: | Treatment of Alzheimer's disease in patients with early symptomatic Alzheimer's disease and confirmed presence of amyloid pathology
Adult dose: | 700 mg administered as an intravenous infusion every 4 weeks, following a loading dose of 1,400 mg (administered as two infusions of 700 mg each, given 2 weeks apart)
Pediatric dose: | Not applicable; safety and efficacy in pediatric populations have not been established
Side effects: | Co
Drug Class
Monoclonal antibody (anti-amyloid beta)
Uses & Indications
Treatment of Alzheimer's disease in patients with early symptomatic Alzheimer's disease and confirmed presence of amyloid pathology
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: Eli Lilly & Co Inc., U.S.A
Package Size
1 Glass Vial (20ml)
Price & Supplier
Price in UAE: AED 3549.50
Dosage Information
Adult Dose
700 mg administered as an intravenous infusion every 4 weeks, following a loading dose of 1,400 mg (administered as two infusions of 700 mg each, given 2 weeks apart)
Pediatric Dose
Not applicable; safety and efficacy in pediatric populations have not been established
Side Effects
Common side effects include infusion-related reactions, amyloid-related imaging abnormalities (ARIA), headache, dizziness, and nausea
Contraindications & Precautions
Known hypersensitivity to donanemab or any component of the formulation; caution in patients with a history of ARIA
Important Warnings
Risk of ARIA, particularly ARIA-E (edema) and ARIA-H (hemorrhage); monitor patients with MRI before and during treatment; potential for serious infusion-related reactions; use caution in patients with cardiovascular conditions
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.