About Doravirine
            
            Class: | Non-nucleoside reverse transcriptase inhibitor (NNRTI)  
Use: | Treatment of HIV-1 infection in combination with other antiretroviral agents in adults and pediatric patients aged 12 years and older weighing at least 40 kg.  
Adult dose: | 100 mg once daily, taken orally with or without food.  
Pediatric dose: | Not established for patients under 12 years or weighing less than 40 kg.  
Side effects: | Common side effects include nausea, diarrhea, fatigue, headache, and rash.  
Contraindi
         
        
            
                
                
                    
                        Drug Class
                    
                    Non-nucleoside reverse transcriptase inhibitor (NNRTI)
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of HIV-1 infection in combination with other antiretroviral agents in adults and pediatric patients aged 12 years and older weighing at least 40 kg.
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature (20°C to 25°C or 68°F to 77°F) in a tightly closed container, protected from moisture and light.
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Merck Sharp & Dohme B.V., NETHERLANDS
                    
                    
                    Package Size
                    30's
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 2220.50
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        100 mg once daily, taken orally with or without food.
                    
                    
                        Pediatric Dose
                    
                    
                        Not established for patients under 12 years or weighing less than 40 kg.
                    
                 
                
                
                    
                        Side Effects
                    
                    Common side effects include nausea, diarrhea, fatigue, headache, and rash.
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Hypersensitivity to doravirine or any component of the formulation; co-administration with strong inducers of CYP3A (e.g., rifampin, St. John's wort).
         
        
        
            
                Important Warnings
            
            Risk of serious skin reactions; monitor for signs of rash; may cause hepatotoxicity; not recommended for use in patients with severe hepatic impairment; potential for drug interactions due to CYP450 metabolism.
         
        
        
        
        
        
            
                Related Medicines in Same Category
            
            
                See also: Other Non-nucleoside reverse transcriptase inhibitor (NNRTI) medicines available in UAE pharmacies
            
            
            
                Etravirine
            
            
         
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.