About Dupilumab
Class: | Monoclonal antibody (IL-4 and IL-13 inhibitor)
Use: | Treatment of moderate to severe asthma, chronic rhinosinusitis with nasal polyps, atopic dermatitis, and eosinophilic esophagitis
Adult dose: | Initial dose of 600 mg (two 300 mg injections) followed by 300 mg every two weeks
Pediatric dose: | For patients aged 6 years and older with atopic dermatitis: initial dose of 600 mg (two 300 mg injections), followed by 300 mg every four weeks; for asthma: 200 mg or 400 mg every two wee
Drug Class
Monoclonal antibody (IL-4 and IL-13 inhibitor)
Uses & Indications
Treatment of moderate to severe asthma, chronic rhinosinusitis with nasal polyps, atopic dermatitis, and eosinophilic esophagitis
Storage Requirements
Store in the refrigerator (2°C to 8°C); do not freeze; may be stored at room temperature (up to 25°C) for up to 14 days
Manufacturer & Packaging
Manufacturer: REGENERON PHARMACEUTICALS, INC., U.S.A
Package Size
2ml Prefilled Syringe x 2
Price & Supplier
Price in UAE: AED 6751.00
Dosage Information
Adult Dose
Initial dose of 600 mg (two 300 mg injections) followed by 300 mg every two weeks
Pediatric Dose
For patients aged 6 years and older with atopic dermatitis: initial dose of 600 mg (two 300 mg injections), followed by 300 mg every four weeks; for asthma: 200 mg or 400 mg every two weeks depending on weight
Side Effects
Injection site reactions, headache, throat pain, fatigue, and conjunctivitis
Contraindications & Precautions
Hypersensitivity to dupilumab or any component of the formulation; active infections (e.g., tuberculosis) should be treated before initiation
Important Warnings
Risk of hypersensitivity reactions; may increase risk of infections; monitor for eosinophilia; not recommended for use in patients with active or untreated infections
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.