About Elbasvir,Grazoprevir
Class: | Antiviral agent (HCV NS5A inhibitor and HCV NS3/4A protease inhibitor)
Use: | Treatment of chronic hepatitis C virus (HCV) infection in adults and pediatric patients aged 12 years and older with specific genotypes (GT 1 and GT 4)
Adult dose: | One tablet (Elbasvir 50 mg/Grazoprevir 100 mg) taken orally once daily with or without food
Pediatric dose: | Not established for patients under 12 years; for patients aged 12 to 17 years, dosing is based on weight and should be determined b
Drug Class
Antiviral agent (HCV NS5A inhibitor and HCV NS3/4A protease inhibitor)
Uses & Indications
Treatment of chronic hepatitis C virus (HCV) infection in adults and pediatric patients aged 12 years and older with specific genotypes (GT 1 and GT 4)
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Merck Canada Inc., CANADA
Package Size
28s Tablets (2 x 14s count child-resistant dose packs)
Price & Supplier
Price in UAE: AED 71592.50
Dosage Information
Adult Dose
One tablet (Elbasvir 50 mg/Grazoprevir 100 mg) taken orally once daily with or without food
Pediatric Dose
Not established for patients under 12 years; for patients aged 12 to 17 years, dosing is based on weight and should be determined by a healthcare provider
Side Effects
Fatigue, headache, nausea, diarrhea, and elevated liver enzymes
Contraindications & Precautions
Severe hepatic impairment (Child-Pugh Class C), co-administration with strong CYP3A inducers (e.g., rifampin, St. John's Wort), and hypersensitivity to Elbasvir or Grazoprevir
Important Warnings
Risk of hepatitis B virus reactivation in patients with a history of HBV infection; monitor liver function during and after treatment; potential for drug interactions with other medications metabolized by CYP enzymes
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.