Back to Search

Elexacaftor (morning),Tezacaftor (Morning),Ivacaftor (Morning),Ivacaftor (Night) – Uses, Dosage, and Brands in UAE

Brand Name: TRIKAFTA

Strength: 100 mg,50 mg,75 mg,150 mg | Form: Tablets

Price in UAE: AED 100855.44

Available in UAE pharmacies

About Elexacaftor (morning),Tezacaftor (Morning),Ivacaftor (Morning),Ivacaftor (Night)

Class: | Cystic fibrosis transmembrane conductance regulator (CFTR) modulator Use: | Treatment of cystic fibrosis in patients aged 12 years and older with specific mutations in the CFTR gene (e.g., F508del mutation) Adult dose: | Elexacaftor 100 mg + Tezacaftor 50 mg + Ivacaftor 75 mg orally once daily in the morning; Ivacaftor 150 mg orally at night Pediatric dose: | Not established for patients under 12 years; dosing for patients 12 years and older follows adult dosing Side effects: |

Drug Class

Cystic fibrosis transmembrane conductance regulator (CFTR) modulator

Uses & Indications

Treatment of cystic fibrosis in patients aged 12 years and older with specific mutations in the CFTR gene (e.g., F508del mutation)

Storage Requirements

Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture

Manufacturer & Packaging

Manufacturer: Vertex Pharmaceuticals Inc, U.S.A

Package Size

56 orange tablets (Elexa 100,Teza 50, Iva 75) Plus 28 blue tablets (Iva 150)

Price & Supplier

Price in UAE: AED 100855.44

Dosage Information

Adult Dose

Elexacaftor 100 mg + Tezacaftor 50 mg + Ivacaftor 75 mg orally once daily in the morning; Ivacaftor 150 mg orally at night

Pediatric Dose

Not established for patients under 12 years; dosing for patients 12 years and older follows adult dosing

Side Effects

Common side effects include headache, abdominal pain, diarrhea, nausea, and elevated liver enzymes

Contraindications & Precautions

Hypersensitivity to any component of the formulation; caution in patients with liver impairment

Important Warnings

Risk of liver enzyme elevation; monitor liver function tests; may cause respiratory effects; not recommended for patients with advanced liver disease

Related Medicines in Same Category

See also: Other Cystic fibrosis transmembrane conductance regulator (CFTR) modulator medicines available in UAE pharmacies

ELEXACAFTOR MORNING,Tezacaftor (Morning),Ivacaftor (Morning),Ivacaftor (Night) Ivacaftor,Lumacaftor Ivacaftor,Tezacaftor Lumacaftor,Ivacaftor Lumacaftor,Ivacaftor Lumacaftor,Ivacaftor

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

View All Cystic fibrosis transmembrane conductance regulator (CFTR) modulator Medicines Browse All Categories