About ENASIDENIB
Class: | Antineoplastic agent, IDH2 inhibitor
Use: | Treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with an IDH2 mutation
Adult dose: | 100 mg orally once daily; may be adjusted based on tolerance and response
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Nausea, diarrhea, fatigue, vomiting, elevated liver enzymes, differentiation syndrome
Contraindications: | Hypersensitivity to enasidenib or any compo
Drug Class
Antineoplastic agent, IDH2 inhibitor
Uses & Indications
Treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with an IDH2 mutation
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F)
Manufacturer & Packaging
Manufacturer: Celgene Corporation, U.S.A
Package Size
30'S
Price & Supplier
Price in UAE: AED 143925.00
Dosage Information
Adult Dose
100 mg orally once daily; may be adjusted based on tolerance and response
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Nausea, diarrhea, fatigue, vomiting, elevated liver enzymes, differentiation syndrome
Contraindications & Precautions
Hypersensitivity to enasidenib or any component of the formulation; pregnancy (due to potential fetal harm)
Important Warnings
Risk of differentiation syndrome; monitor for signs and symptoms; liver function tests should be performed prior to and during treatment; potential for fetal harm if taken during pregnancy
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.