About fam Trastuzumab deruxtecan nxki
Class: | Antineoplastic agent, HER2-targeted antibody-drug conjugate
Use: | Treatment of adult patients with unresectable or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting
Adult dose: | 5.4 mg/kg administered as an intravenous infusion once every three weeks
Pediatric dose: | Safety and efficacy have not been established in pediatric patients
Side effects: | Nausea, fatigue, alopecia, decreased appetite, diarr
Drug Class
Antineoplastic agent, HER2-targeted antibody-drug conjugate
Uses & Indications
Treatment of adult patients with unresectable or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting
Storage Requirements
Store refrigerated at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: Daiichi Sankyo Inc., U.S.A
Package Size
100mg Vial
Price & Supplier
Price in UAE: AED 23460.00
Dosage Information
Adult Dose
5.4 mg/kg administered as an intravenous infusion once every three weeks
Pediatric Dose
Safety and efficacy have not been established in pediatric patients
Side Effects
Nausea, fatigue, alopecia, decreased appetite, diarrhea, vomiting, and interstitial lung disease (ILD)
Contraindications & Precautions
Known hypersensitivity to trastuzumab deruxtecan or any component of the formulation; severe interstitial lung disease or pneumonitis
Important Warnings
Risk of ILD/pneumonitis; monitor for respiratory symptoms; may cause fetal harm; perform pregnancy testing in females of reproductive potential before treatment
Related Medicines in Same Category
See also: Other Antineoplastic agent, HER2-targeted antibody-drug conjugate medicines available in UAE pharmacies
Trastuzumab Deruxtecan (ENHERTU)
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.