About Fenofibrate,Simvastatin
Class: | Antihyperlipidemic agent (Fenofibrate) and HMG-CoA reductase inhibitor (Simvastatin)
Use: | Used to lower cholesterol and triglyceride levels in patients with hyperlipidemia, to reduce the risk of cardiovascular events in patients with atherosclerotic cardiovascular disease or diabetes.
Adult dose: | Fenofibrate: 145 mg once daily; Simvastatin: 20 mg once daily, taken in the evening.
Pediatric dose: | Not established for children under 10 years; for children 10-17 years, Simvastat
Drug Class
Antihyperlipidemic agent (Fenofibrate) and HMG-CoA reductase inhibitor (Simvastatin)
Uses & Indications
Used to lower cholesterol and triglyceride levels in patients with hyperlipidemia, to reduce the risk of cardiovascular events in patients with atherosclerotic cardiovascular disease or diabetes.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, away from moisture and light.
Manufacturer & Packaging
Manufacturer: Abbott Laboratories Limited, UNITED KINGDOM
Package Size
30s
Price & Supplier
Price in UAE: AED 53.50
Dosage Information
Adult Dose
Fenofibrate: 145 mg once daily; Simvastatin: 20 mg once daily, taken in the evening.
Pediatric Dose
Not established for children under 10 years; for children 10-17 years, Simvastatin can be used at a dose of 5-20 mg once daily based on LDL-C levels.
Side Effects
Common side effects include headache, abdominal pain, nausea, muscle pain, and elevated liver enzymes.
Contraindications & Precautions
Contraindicated in patients with active liver disease, unexplained persistent elevations of liver enzymes, pregnancy, lactation, and hypersensitivity to either component.
Important Warnings
Risk of myopathy and rhabdomyolysis, especially in patients with renal impairment, elderly patients, and those on high doses of Simvastatin. Monitor liver function tests before and during therapy.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.