About Finerenone
Class: | Non-steroidal mineralocorticoid receptor antagonist (MRA)
Use: | Finerenone (KERENDIA) is indicated to reduce the risk of sustained eGFR decline, end-stage kidney disease, cardiovascular death, non-fatal myocardial infarction, and hospitalization for heart failure in adult patients with chronic kidney disease (CKD) associated with type 2 diabetes.
Adult dose: | The recommended starting dose is 10 mg once daily. The dose may be increased to 20 mg once daily based on the patient's serum
Drug Class
Non-steroidal mineralocorticoid receptor antagonist (MRA)
Uses & Indications
Finerenone (KERENDIA) is indicated to reduce the risk of sustained eGFR decline, end-stage kidney disease, cardiovascular death, non-fatal myocardial infarction, and hospitalization for heart failure in adult patients with chronic kidney disease (CKD) associated with type 2 diabetes.
Storage Requirements
Store at room temperature, between 20°C to 25°C (68°F to 77°F), with excursions permitted to 15°C to 30°C (59°F to 86°F).
Manufacturer & Packaging
Manufacturer: Bayer AG, GERMANY
Package Size
28's (14's Blister x 2)
Price & Supplier
Price in UAE: AED 428.50
Dosage Information
Adult Dose
The recommended starting dose is 10 mg once daily. The dose may be increased to 20 mg once daily based on the patient's serum potassium levels and kidney function.
Pediatric Dose
Safety and efficacy in pediatric patients have not been established; therefore, no dosing information is available for this population.
Side Effects
Common side effects include hyperkalemia, hypotension, and hyponatremia.
Contraindications & Precautions
Finerenone is contraindicated in patients with serum potassium >5.0 mEq/L at initiation, those with adrenal insufficiency, and those with concomitant use of strong CYP3A4 inhibitors.
Important Warnings
Monitor serum potassium levels periodically and adjust the dose accordingly to avoid hyperkalemia. Use caution in patients with impaired renal function or those taking other medications that increase serum potassium.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.