About Fludarabine Phosphate
Class: | Antineoplastic agent, Purine analog
Use: | Treatment of B-cell chronic lymphocytic leukemia (CLL) in patients who have not responded to or have progressed during treatment with at least one standard alkylating agent-containing regimen.
Adult dose: | The recommended adult dose is 40 mg/m² orally once daily for 5 consecutive days every 28 days.
Pediatric dose: | Safety and efficacy in pediatric patients have not been established; therefore, dosing information is not available.
Sid
Drug Class
Antineoplastic agent, Purine analog
Uses & Indications
Treatment of B-cell chronic lymphocytic leukemia (CLL) in patients who have not responded to or have progressed during treatment with at least one standard alkylating agent-containing regimen.
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light and moisture.
Manufacturer & Packaging
Manufacturer: Bayer AG, GERMANY
Package Size
20's
Price & Supplier
Price in UAE: AED 4117.00
Dosage Information
Adult Dose
The recommended adult dose is 40 mg/m² orally once daily for 5 consecutive days every 28 days.
Pediatric Dose
Safety and efficacy in pediatric patients have not been established; therefore, dosing information is not available.
Side Effects
Common side effects include myelosuppression, fever, infection, nausea, vomiting, diarrhea, fatigue, cough, and rash.
Contraindications & Precautions
Contraindicated in patients with severe renal impairment (creatinine clearance < 30 mL/min), and in those with hypersensitivity to fludarabine phosphate or any component of the formulation.
Important Warnings
Fludarabine phosphate can cause severe bone marrow suppression, increased risk of opportunistic infections, autoimmune hemolytic anemia, and neurotoxicity. It should be used with caution in patients with renal impairment and requires regular monitoring of blood counts.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.