About Givosiran
Class: | RNA interference therapeutic
Use: | Treatment of acute hepatic porphyria (AHP) in adults
Adult dose: | 2.5 mg/kg subcutaneously once every month
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Injection site reactions, nausea, abdominal pain, fatigue, headache
Contraindications: | Hypersensitivity to givosiran or any component of the formulation
Storage: | Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; prote
Drug Class
RNA interference therapeutic
Uses & Indications
Treatment of acute hepatic porphyria (AHP) in adults
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: Alnylam Netherlands B.V., Netherlands
Package Size
2mL Vial
Price & Supplier
Price in UAE: AED 192011.10
Dosage Information
Adult Dose
2.5 mg/kg subcutaneously once every month
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Injection site reactions, nausea, abdominal pain, fatigue, headache
Contraindications & Precautions
Hypersensitivity to givosiran or any component of the formulation
Important Warnings
Risk of liver injury; monitor liver function tests; may cause hypersensitivity reactions; not recommended in patients with severe hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.