About Glecaprevir,Pibrentasvir
Class: | Antiviral agent, Direct-acting antiviral (DAA)
Use: | Treatment of chronic hepatitis C virus (HCV) infection in adults and pediatric patients aged 3 years and older, with or without compensated cirrhosis
Adult dose: | 3 tablets (100 mg glecaprevir and 40 mg pibrentasvir) taken orally once daily with food
Pediatric dose: | For patients aged 3 years and older, the dose is based on weight: weight 17 kg to < 30 kg: 2 tablets (50 mg glecaprevir and 20 mg pibrentasvir) once daily; weig
Drug Class
Antiviral agent, Direct-acting antiviral (DAA)
Uses & Indications
Treatment of chronic hepatitis C virus (HCV) infection in adults and pediatric patients aged 3 years and older, with or without compensated cirrhosis
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Abbvie Ltd., UNITED KINGDOM
Package Size
84s
Price & Supplier
Price in UAE: AED 77349.50
Dosage Information
Adult Dose
3 tablets (100 mg glecaprevir and 40 mg pibrentasvir) taken orally once daily with food
Pediatric Dose
For patients aged 3 years and older, the dose is based on weight: weight 17 kg to < 30 kg: 2 tablets (50 mg glecaprevir and 20 mg pibrentasvir) once daily; weight ≥ 30 kg: 3 tablets (100 mg glecaprevir and 40 mg pibrentasvir) once daily
Side Effects
Fatigue, headache, nausea, diarrhea, and elevated liver enzymes
Contraindications & Precautions
Co-administration with strong CYP3A inhibitors (e.g., rifampin, carbamazepine) or strong CYP3A inducers (e.g., St. John's Wort); hypersensitivity to any component of the formulation
Important Warnings
Risk of hepatitis B virus reactivation in patients with a history of HBV infection; monitor liver function during and after treatment; not recommended for use in patients with severe hepatic impairment (Child-Pugh Class C)
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.