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Ifosfamide – Uses, Dosage, and Brands in UAE

Brand Name: HOLOXAN
Strength: 1000 mg | Form: Powder For Solution For Intravenous Injection
Price in UAE: AED 150.00
Available in UAE pharmacies

About Ifosfamide

Class: | Alkylating agent, Antineoplastic agent Use: | Ifosfamide is used primarily for the treatment of testicular cancer and is also used in combination with other chemotherapy agents for various types of cancer, including sarcomas and lymphomas. Adult dose: | The typical adult dose is 1.2 g/m² intravenously once daily for 5 consecutive days, repeated every 3 weeks. Dosage may vary based on specific treatment protocols and patient factors. Pediatric dose: | Pediatric dosing is highly ind

Drug Class

Alkylating agent, Antineoplastic agent

Uses & Indications

Ifosfamide is used primarily for the treatment of testicular cancer and is also used in combination with other chemotherapy agents for various types of cancer, including sarcomas and lymphomas.

Storage Requirements

Store at controlled room temperature, between 20°C to 25°C (68°F to 77°F). Protect from light and moisture. Reconstituted solutions should be used within 24 hours if stored at room temperature or within 6 days if refrigerated.

Manufacturer & Packaging

Manufacturer: Baxter S.A., BELGIUM

Package Size

Dry Powder Vial

Price & Supplier

Price in UAE: AED 150.00

Dosage Information

Adult Dose

The typical adult dose is 1.2 g/m² intravenously once daily for 5 consecutive days, repeated every 3 weeks. Dosage may vary based on specific treatment protocols and patient factors.

Pediatric Dose

Pediatric dosing is highly individualized and should be determined by a specialist based on the type of cancer, the child's size, and overall health.

Side Effects

Common side effects include nausea, vomiting, hair loss, low blood cell counts, and risk of infection. Hemorrhagic cystitis, neurotoxicity, and renal toxicity are also notable side effects.

Contraindications & Precautions

Contraindicated in patients with known hypersensitivity to ifosfamide or any component of the formulation. Caution is advised in patients with renal impairment, hepatic impairment, or bone marrow suppression.

Important Warnings

Ifosfamide can cause severe bone marrow suppression, leading to increased risk of infection and bleeding. It can also cause severe bladder toxicity, including hemorrhagic cystitis, and requires co-administration with mesna and adequate hydration. Neurotoxicity, including encephalopathy, is a serious risk. Regular monitoring of blood counts, renal function, and liver function is necessary.

Other Brands & Strengths Available in UAE

Different brands and strengths of Ifosfamide available in UAE pharmacies:

HOLOXAN 1 g Powder For Solution For Injection HOLOXAN 1 g Powder For Solution For Injection HOLOXAN 1000 mg Powder For Solution For Intravenous Injection

Related Medicines in Same Category

See also: Other Alkylating agent, Antineoplastic agent medicines available in UAE pharmacies

Cyclophosphamide Cyclophosphamide Cyclophosphamide

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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