About Ipilimumab
Class: | Monoclonal antibody (CTLA-4 inhibitor)
Use: | Treatment of unresectable or metastatic melanoma, adjuvant treatment of melanoma, and treatment of certain types of metastatic colorectal cancer in combination with nivolumab
Adult dose: | 3 mg/kg IV every 3 weeks for 4 doses, then 10 mg/kg IV every 2 weeks or 3 mg/kg IV every 2 weeks depending on the indication
Pediatric dose: | Safety and efficacy not established in pediatric patients; use is not recommended
Side effects: | Fatigue
Drug Class
Monoclonal antibody (CTLA-4 inhibitor)
Uses & Indications
Treatment of unresectable or metastatic melanoma, adjuvant treatment of melanoma, and treatment of certain types of metastatic colorectal cancer in combination with nivolumab
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; may be stored at room temperature for up to 24 hours before use
Manufacturer & Packaging
Manufacturer: Bristol Myers Squibb Company, U.S.A
Package Size
40ml Glass Vial
Price & Supplier
Price in UAE: AED 110252.00
Dosage Information
Adult Dose
3 mg/kg IV every 3 weeks for 4 doses, then 10 mg/kg IV every 2 weeks or 3 mg/kg IV every 2 weeks depending on the indication
Pediatric Dose
Safety and efficacy not established in pediatric patients; use is not recommended
Side Effects
Fatigue, diarrhea, rash, pruritus, colitis, hepatitis, endocrinopathies (e.g., thyroid dysfunction), and infusion-related reactions
Contraindications & Precautions
History of severe hypersensitivity to ipilimumab or any component of the formulation; contraindicated in patients with autoimmune diseases or those receiving immunosuppressive therapy
Important Warnings
Risk of severe immune-mediated adverse reactions; monitor for signs and symptoms of colitis, hepatitis, endocrinopathies, and pneumonitis; may require corticosteroid treatment for severe reactions; not recommended for patients with active infections or those who have received prior organ transplant
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.