About Irinotecan anhydrous free base
Class: | Antineoplastic agent, Topoisomerase I inhibitor
Use: | Treatment of metastatic pancreatic cancer in combination with fluorouracil and leucovorin in patients who have previously received gemcitabine-based therapy
Adult dose: | 1.0 mg/m² administered as an intravenous infusion over 90 minutes every 2 weeks, in combination with fluorouracil and leucovorin
Pediatric dose: | Safety and efficacy have not been established in pediatric patients; not recommended for use in this population
Drug Class
Antineoplastic agent, Topoisomerase I inhibitor
Uses & Indications
Treatment of metastatic pancreatic cancer in combination with fluorouracil and leucovorin in patients who have previously received gemcitabine-based therapy
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: LES LABORATOIRES SERIVER {Suresnes Cedex France), France
Package Size
1 Glass Vial (10ml)
Price & Supplier
Price in UAE: AED 4416.00
Dosage Information
Adult Dose
1.0 mg/m² administered as an intravenous infusion over 90 minutes every 2 weeks, in combination with fluorouracil and leucovorin
Pediatric Dose
Safety and efficacy have not been established in pediatric patients; not recommended for use in this population
Side Effects
Diarrhea, nausea, vomiting, fatigue, neutropenia, abdominal pain, and increased liver enzymes
Contraindications & Precautions
Hypersensitivity to irinotecan or any component of the formulation; severe bone marrow suppression; diarrhea; pregnancy and lactation
Important Warnings
Risk of severe diarrhea, myelosuppression, and potential for life-threatening infections; monitor for signs of dehydration and infection; caution in patients with hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.