About Isavuconazole
Class: | Antifungal agent (Triazole antifungal)
Use: | Treatment of invasive aspergillosis and invasive mucormycosis in adults.
Adult dose: | Loading dose: 372 mg (equivalent to 200 mg of isavuconazole) every 8 hours for 6 doses (48 hours), followed by a maintenance dose of 372 mg once daily.
Pediatric dose: | Safety and efficacy in pediatric patients have not been established.
Side effects: | Common side effects include nausea, vomiting, diarrhea, headache, elevated liver enzymes, hypokalemia,
Drug Class
Antifungal agent (Triazole antifungal)
Uses & Indications
Treatment of invasive aspergillosis and invasive mucormycosis in adults.
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).
Manufacturer & Packaging
Manufacturer: Al Hikma Pharmaceuticals, JORDAN
Package Size
14s
Price & Supplier
Price in UAE: AED 3619.00
Dosage Information
Adult Dose
Loading dose: 372 mg (equivalent to 200 mg of isavuconazole) every 8 hours for 6 doses (48 hours), followed by a maintenance dose of 372 mg once daily.
Pediatric Dose
Safety and efficacy in pediatric patients have not been established.
Side Effects
Common side effects include nausea, vomiting, diarrhea, headache, elevated liver enzymes, hypokalemia, and peripheral edema.
Contraindications & Precautions
Contraindicated in patients with known hypersensitivity to isavuconazole or any of its components. Contraindicated with strong CYP3A4 inhibitors (e.g., ketoconazole, high-dose ritonavir) and inducers (e.g., rifampin, carbamazepine, St. John's wort).
Important Warnings
Hepatic adverse reactions: Monitor liver function tests. Infusion-related reactions: Discontinue if severe reactions occur. Embryo-fetal toxicity: May cause fetal harm; advise females of reproductive potential to use effective contraception. QT interval shortening: Use with caution in patients with familial short QT syndrome.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.