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Ivacaftor – Uses, Dosage, and Brands in UAE

Brand Name: KALYDECO

Strength: 150 mg | Form: Tablets

Price in UAE: AED 120153.00

Available in UAE pharmacies

About Ivacaftor

Class: | Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator Use: | Treatment of cystic fibrosis in patients aged 2 years and older with specific mutations in the CFTR gene (G551D and others) Adult dose: | 150 mg orally every 12 hours Pediatric dose: | 150 mg orally every 12 hours for patients aged 6 years and older; for patients aged 2 to <6 years, dosing is based on weight (e.g., 50 mg for 5 kg to <15 kg, 75 mg for 15 kg to <25 kg, and 100 mg for 25 kg to <30 kg) Sid

Drug Class

Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator

Uses & Indications

Treatment of cystic fibrosis in patients aged 2 years and older with specific mutations in the CFTR gene (G551D and others)

Storage Requirements

Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture

Manufacturer & Packaging

Manufacturer: Vertex Pharmaceuticals Limited, UNITED KINGDOM

Package Size

56's Blister Pack

Price & Supplier

Price in UAE: AED 120153.00

Dosage Information

Adult Dose

150 mg orally every 12 hours

Pediatric Dose

150 mg orally every 12 hours for patients aged 6 years and older; for patients aged 2 to <6 years, dosing is based on weight (e.g., 50 mg for 5 kg to <15 kg, 75 mg for 15 kg to <25 kg, and 100 mg for 25 kg to <30 kg)

Side Effects

Common side effects include headache, nausea, diarrhea, upper respiratory tract infections, and abdominal pain

Contraindications & Precautions

Hypersensitivity to ivacaftor or any component of the formulation; caution in patients with hepatic impairment

Important Warnings

Risk of elevated liver enzymes; monitor liver function tests before and during treatment; potential for drug interactions with strong CYP3A inhibitors or inducers

Other Brands & Strengths Available in UAE

Different brands and strengths of Ivacaftor available in UAE pharmacies:

KALYDECO 150 mg Tablets KALYDECO 150 mg Tablets KALYDECO 25 mg Granules For Oral Administration KALYDECO 50 mg Granules For Oral Administration KALYDECO 75 mg Granules For Oral Administration

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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