About Ivacaftor,Tezacaftor
Class: | Cystic fibrosis transmembrane conductance regulator (CFTR) modulator
Use: | Treatment of cystic fibrosis in patients aged 12 years and older with specific mutations in the CFTR gene (including F508del mutation)
Adult dose: | Ivacaftor 150 mg and Tezacaftor 100 mg taken orally once daily with fat-containing food
Pediatric dose: | Not established for patients under 12 years; dosing for patients aged 12 years and older is the same as adults
Side effects: | Headache, nausea, diarrhe
Drug Class
Cystic fibrosis transmembrane conductance regulator (CFTR) modulator
Uses & Indications
Treatment of cystic fibrosis in patients aged 12 years and older with specific mutations in the CFTR gene (including F508del mutation)
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture
Manufacturer & Packaging
Manufacturer: Vertex Pharmaceuticals Limited, UNITED KINGDOM
Package Size
56s
Price & Supplier
Price in UAE: AED 94539.20
Dosage Information
Adult Dose
Ivacaftor 150 mg and Tezacaftor 100 mg taken orally once daily with fat-containing food
Pediatric Dose
Not established for patients under 12 years; dosing for patients aged 12 years and older is the same as adults
Side Effects
Headache, nausea, diarrhea, abdominal pain, rash, and elevated liver enzymes
Contraindications & Precautions
Hypersensitivity to Ivacaftor, Tezacaftor, or any component of the formulation; caution in patients with hepatic impairment
Important Warnings
Risk of liver injury; monitor liver function tests prior to and during treatment; may cause cataracts in pediatric patients; use caution in patients with a history of liver disease or those taking medications that affect liver enzymes
Related Medicines in Same Category
See also: Other Cystic fibrosis transmembrane conductance regulator (CFTR) modulator medicines available in UAE pharmacies
ELEXACAFTOR MORNING,Tezacaftor (Morning),Ivacaftor (Morning),Ivacaftor (Night)
Elexacaftor (morning),Tezacaftor (Morning),Ivacaftor (Morning),Ivacaftor (Night)
Ivacaftor,Lumacaftor
Lumacaftor,Ivacaftor
Lumacaftor,Ivacaftor
Lumacaftor,Ivacaftor
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.