About Macitentan
Class: | Endothelin receptor antagonist
Use: | Treatment of pulmonary arterial hypertension (PAH) to improve exercise ability and delay clinical worsening
Adult dose: | 10 mg orally once daily
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Headache, anemia, peripheral edema, nasal congestion, and elevated liver enzymes
Contraindications: | Pregnancy (category X), hypersensitivity to macitentan or any component of the formulation, severe hepa
Drug Class
Endothelin receptor antagonist
Uses & Indications
Treatment of pulmonary arterial hypertension (PAH) to improve exercise ability and delay clinical worsening
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Actelion Pharmaceuticals Ltd., SWITZERLAND
Package Size
30s (15s Blister x 2)
Price & Supplier
Price in UAE: AED 16944.00
Dosage Information
Adult Dose
10 mg orally once daily
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Headache, anemia, peripheral edema, nasal congestion, and elevated liver enzymes
Contraindications & Precautions
Pregnancy (category X), hypersensitivity to macitentan or any component of the formulation, severe hepatic impairment
Important Warnings
Risk of teratogenic effects in pregnancy; liver function should be monitored; may cause anemia; not recommended for use in patients with severe hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.