About Maralixibat
Class: | Bile acid transport inhibitor
Use: | Treatment of cholestatic pruritus in patients with Alagille syndrome aged 1 year and older
Adult dose: | Not established; primarily indicated for pediatric use
Pediatric dose: | Initial dose of 1 mg/kg once daily; may be increased to a maximum of 9.5 mg once daily based on clinical response and tolerability
Side effects: | Diarrhea, abdominal pain, vomiting, fatigue, and decreased appetite
Contraindications: | Hypersensitivity to maralixiba
Drug Class
Bile acid transport inhibitor
Uses & Indications
Treatment of cholestatic pruritus in patients with Alagille syndrome aged 1 year and older
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from light; keep tightly closed
Manufacturer & Packaging
Manufacturer: Mirum Pharmaceuticals, Inc., Canada
Package Size
30 mL
Price & Supplier
Price in UAE: AED 172598.90
Dosage Information
Adult Dose
Not established; primarily indicated for pediatric use
Pediatric Dose
Initial dose of 1 mg/kg once daily; may be increased to a maximum of 9.5 mg once daily based on clinical response and tolerability
Side Effects
Diarrhea, abdominal pain, vomiting, fatigue, and decreased appetite
Contraindications & Precautions
Hypersensitivity to maralixibat or any component of the formulation; severe liver impairment
Important Warnings
Risk of severe diarrhea; monitor for dehydration; not recommended for use in patients with severe hepatic impairment; use caution in patients with a history of bowel obstruction or significant gastrointestinal disease
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.