About Metformin Hydrochloride,Vildagliptin
Class: | Antidiabetic agent (Biguanide and Dipeptidyl Peptidase-4 (DPP-4) inhibitor)
Use: | Management of type 2 diabetes mellitus in adults, particularly in patients who are overweight or obese, to improve glycemic control alongside diet and exercise.
Adult dose: | Typically, the starting dose is 500 mg Metformin hydrochloride and 50 mg Vildagliptin once daily, which may be increased to a maximum of 1000 mg Metformin and 100 mg Vildagliptin per day based on glycemic response.
Pediatric do
Drug Class
Antidiabetic agent (Biguanide and Dipeptidyl Peptidase-4 (DPP-4) inhibitor)
Uses & Indications
Management of type 2 diabetes mellitus in adults, particularly in patients who are overweight or obese, to improve glycemic control alongside diet and exercise.
Storage Requirements
Store at room temperature (15°C to 30°C or 59°F to 86°F) in a tightly closed container, protected from moisture and light.
Manufacturer & Packaging
Manufacturer: Novartis Pharma AG, SWITZERLAND
Package Size
60's (10's Blister x 6)
Price & Supplier
Price in UAE: AED 223.00
Dosage Information
Adult Dose
Typically, the starting dose is 500 mg Metformin hydrochloride and 50 mg Vildagliptin once daily, which may be increased to a maximum of 1000 mg Metformin and 100 mg Vildagliptin per day based on glycemic response.
Pediatric Dose
Not established for children under 18 years; use in pediatric patients should be based on clinical judgment and individual assessment.
Side Effects
Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), headache, dizziness, and hypoglycemia (especially when used with other antidiabetic agents).
Contraindications & Precautions
Contraindicated in patients with severe renal impairment (eGFR < 30 mL/min), acute or chronic metabolic acidosis, including diabetic ketoacidosis, and hypersensitivity to either component.
Important Warnings
Risk of lactic acidosis, particularly in patients with renal impairment, liver disease, or conditions leading to hypoxia; monitor renal function regularly. Caution in patients with heart failure or those who consume excessive alcohol.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.