About Methylprednisolone hemisuccinate USP 633.60 mg equivalent to Methylprednisolone 500 mg
Class: | Corticosteroid
Use: | Methylprednisolone hemisuccinate is used for the treatment of various inflammatory and autoimmune conditions, including but not limited to allergies, asthma, rheumatoid arthritis, lupus, and certain skin disorders. It is also used in the management of acute exacerbations of multiple sclerosis and for the treatment of certain types of shock.
Adult dose: | The typical adult dose for Methylprednisolone hemisuccinate is 500 mg to 1 g administered intravenously, dep
Drug Class
Corticosteroid
Uses & Indications
Methylprednisolone hemisuccinate is used for the treatment of various inflammatory and autoimmune conditions, including but not limited to allergies, asthma, rheumatoid arthritis, lupus, and certain skin disorders. It is also used in the management of acute exacerbations of multiple sclerosis and for the treatment of certain types of shock.
Storage Requirements
Store at controlled room temperature (20-25°C or 68-77°F). Protect from light and moisture. Once reconstituted, the solution should be used immediately or stored in the refrigerator for a limited time as per specific guidelines.
Manufacturer & Packaging
Manufacturer: HIKMA PHARMACEUTICALS, AMMMAN, JORDAN, Jordan
Package Size
1 Glass Vial
Price & Supplier
Price in UAE: AED 34.00
Dosage Information
Adult Dose
The typical adult dose for Methylprednisolone hemisuccinate is 500 mg to 1 g administered intravenously, depending on the severity of the condition being treated. Dosing may vary based on clinical response and specific indications.
Pediatric Dose
The pediatric dose is typically based on body weight or body surface area and should be determined by a healthcare provider. A common range is 0.5 to 1 mg/kg/day, not exceeding adult doses.
Side Effects
Common side effects include insomnia, mood changes, increased appetite, weight gain, fluid retention, elevated blood sugar levels, and gastrointestinal disturbances. Long-term use may lead to more serious effects such as adrenal suppression, osteoporosis, and increased risk of infections.
Contraindications & Precautions
Contraindications include systemic fungal infections, known hypersensitivity to methylprednisolone or any component of the formulation, and certain viral infections (e.g., herpes simplex keratitis). Caution is advised in patients with peptic ulcer disease, diabetes, hypertension, or renal insufficiency.
Important Warnings
Important safety warnings include the risk of serious infections, potential for adrenal insufficiency upon abrupt discontinuation, and the need for gradual tapering of doses after prolonged therapy. Patients should be monitored for signs of infection and other serious side effects during treatment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.