About Metreleptin
Class: | Hormone replacement therapy (leptin analog)
Use: | Treatment of leptin deficiency in patients with congenital or acquired generalized lipodystrophy
Adult dose: | Initial dose of 0.06 mg/kg subcutaneously once daily; may be adjusted based on clinical response and tolerability
Pediatric dose: | Initial dose of 0.06 mg/kg subcutaneously once daily for children aged 2 years and older; adjustments may be made based on clinical response
Side effects: | Hypoglycemia, injection site rea
Drug Class
Hormone replacement therapy (leptin analog)
Uses & Indications
Treatment of leptin deficiency in patients with congenital or acquired generalized lipodystrophy
Storage Requirements
Store lyophilized powder at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; after reconstitution, use within 3 hours if stored at room temperature or within 24 hours if refrigerated
Manufacturer & Packaging
Manufacturer: Amryt Pharma Group, United States of America
Package Size
Vial
Price & Supplier
Price in UAE: AED 14429.40
Dosage Information
Adult Dose
Initial dose of 0.06 mg/kg subcutaneously once daily; may be adjusted based on clinical response and tolerability
Pediatric Dose
Initial dose of 0.06 mg/kg subcutaneously once daily for children aged 2 years and older; adjustments may be made based on clinical response
Side Effects
Hypoglycemia, injection site reactions, headache, abdominal pain, nausea, and increased liver enzymes
Contraindications & Precautions
Known hypersensitivity to metreleptin or any component of the formulation; caution in patients with a history of hypersensitivity reactions
Important Warnings
Risk of serious infections; monitor for signs of pancreatitis; may cause hypoglycemia; not a substitute for insulin in patients with diabetes; potential for development of anti-metreleptin antibodies
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.