About Metyrapone
Class: | Corticosteroid synthesis inhibitor
Use: | Metyrapone is used for diagnostic testing of adrenal function and to treat conditions associated with adrenal insufficiency, particularly in patients with Cushing's syndrome.
Adult dose: | The standard adult dose for diagnostic purposes is 750 mg orally taken at bedtime, with a follow-up plasma cortisol measurement the next morning. For therapeutic use, dosing may vary based on clinical response and should be determined by a healthcare provi
Drug Class
Corticosteroid synthesis inhibitor
Uses & Indications
Metyrapone is used for diagnostic testing of adrenal function and to treat conditions associated with adrenal insufficiency, particularly in patients with Cushing's syndrome.
Storage Requirements
Store at room temperature, away from moisture and heat. Keep out of reach of children.
Manufacturer & Packaging
Manufacturer: Laboratoire HRA Pharma, CANADA
Package Size
100s
Price & Supplier
Price in UAE: AED 3220.00
Dosage Information
Adult Dose
The standard adult dose for diagnostic purposes is 750 mg orally taken at bedtime, with a follow-up plasma cortisol measurement the next morning. For therapeutic use, dosing may vary based on clinical response and should be determined by a healthcare provider.
Pediatric Dose
Safety and efficacy in pediatric patients have not been established; therefore, use in children is not recommended unless under strict medical supervision.
Side Effects
Common side effects include dizziness, headache, nausea, vomiting, abdominal discomfort, and allergic reactions.
Contraindications & Precautions
Metyrapone is contraindicated in patients with hypersensitivity to the drug, adrenal insufficiency without appropriate glucocorticoid replacement, and in pregnancy unless the benefits outweigh the risks.
Important Warnings
Metyrapone may cause adrenal crisis in patients with adrenal insufficiency; monitor for signs of adrenal insufficiency. Use with caution in patients with severe liver disease. Regular monitoring of cortisol levels is recommended during treatment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.