About Antihemophilic Factor (Recombinant) Fc Fusion Protein (Efmoroctocog alfa)
Class: | Hemostatic agent, Factor VIII replacement therapy
Use: | Treatment and prophylaxis of bleeding episodes in patients with hemophilia A (congenital factor VIII deficiency)
Adult dose: | 50 IU/kg body weight for on-demand treatment; 20-40 IU/kg every 3-5 days for prophylaxis, adjusted based on clinical response
Pediatric dose: | 50 IU/kg for on-demand treatment; 20-40 IU/kg every 3-5 days for prophylaxis, adjusted based on clinical response; dosing may vary based on age and weight
Drug Class
Hemostatic agent, Factor VIII replacement therapy
Uses & Indications
Treatment and prophylaxis of bleeding episodes in patients with hemophilia A (congenital factor VIII deficiency)
Storage Requirements
Store in a refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; may be stored at room temperature (up to 25°C or 77°F) for a maximum of 3 months
Manufacturer & Packaging
Manufacturer: Swedish Orphan Biovitrum AB, SWEDEN
Package Size
1 Glass Vial+ 1 Pre-filled Syringe (5 ml Solvent) + 1 Plunger Rod + 1 Vial Adapter + 1 Infusion Set + 2 Swabs + 2 Plasters + 1 Gauze
Price & Supplier
Price in UAE: AED 5256.50
Dosage Information
Adult Dose
50 IU/kg body weight for on-demand treatment; 20-40 IU/kg every 3-5 days for prophylaxis, adjusted based on clinical response
Pediatric Dose
50 IU/kg for on-demand treatment; 20-40 IU/kg every 3-5 days for prophylaxis, adjusted based on clinical response; dosing may vary based on age and weight
Side Effects
Headache, nausea, infusion site reactions, arthralgia, and fever
Contraindications & Precautions
Known hypersensitivity to Efmoroctocog alfa or any component of the formulation; history of severe allergic reactions to factor VIII products
Important Warnings
Risk of thrombosis and thromboembolic events; monitor for signs of allergic reactions; patients with inhibitors to factor VIII may not respond to treatment; use caution in patients with cardiovascular disease or risk factors for thrombosis
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.