About Naloxone Hydrochloride,Oxycodone Hydrochloride
Class: | Opioid analgesic combination (Naloxone Hydrochloride is an opioid antagonist; Oxycodone Hydrochloride is an opioid analgesic)
Use: | Management of severe pain requiring continuous, long-term opioid treatment in patients who are tolerant to opioids
Adult dose: | TARGINACT 10 mg/5 mg: 1 tablet every 12 hours; TARGINACT 20 mg/10 mg: 1 tablet every 12 hours; dosage may be adjusted based on individual patient needs and response
Pediatric dose: | Safety and efficacy not established in p
Drug Class
Opioid analgesic combination (Naloxone Hydrochloride is an opioid antagonist; Oxycodone Hydrochloride is an opioid analgesic)
Uses & Indications
Management of severe pain requiring continuous, long-term opioid treatment in patients who are tolerant to opioids
Storage Requirements
Store at room temperature (15°C to 30°C or 59°F to 86°F); protect from moisture and light; keep out of reach of children
Manufacturer & Packaging
Manufacturer: Napp Pharmaceuticals Ltd., UNITED KINGDOM
Package Size
56's (14's Blister x 4)
Price & Supplier
Price in UAE: AED 671.50
Dosage Information
Adult Dose
TARGINACT 10 mg/5 mg: 1 tablet every 12 hours; TARGINACT 20 mg/10 mg: 1 tablet every 12 hours; dosage may be adjusted based on individual patient needs and response
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children
Side Effects
Common side effects include constipation, nausea, vomiting, dizziness, sedation, headache, dry mouth, and sweating
Contraindications & Precautions
Hypersensitivity to oxycodone, naloxone, or any component of the formulation; severe respiratory depression; acute or severe bronchial asthma; gastrointestinal obstruction; concurrent use with monoamine oxidase inhibitors (MAOIs)
Important Warnings
Risk of addiction, abuse, and misuse; respiratory depression; accidental overdose; naloxone component may precipitate withdrawal in opioid-dependent patients; monitor for signs of opioid overdose, especially in patients with a history of substance use disorder or those receiving high doses of opioids
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.