About Nirmatrelvir,Ritonavir
Class: | Antiviral (Protease Inhibitor Combination)
Use: | Treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years and older weighing at least 40 kg) who are at high risk for progression to severe COVID-19, including hospitalization or death.
Adult dose: | Nirmatrelvir 300 mg (two 150 mg tablets) plus Ritonavir 100 mg (one 100 mg tablet) taken orally twice daily for 5 days.
Pediatric dose: | Not established for patients under 12 years of age or weighing less than
Drug Class
Antiviral (Protease Inhibitor Combination)
Uses & Indications
Treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years and older weighing at least 40 kg) who are at high risk for progression to severe COVID-19, including hospitalization or death.
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F) in a tightly closed container. Protect from moisture and light.
Manufacturer & Packaging
Manufacturer: Pfizer Limited, UNITED KINGDOM
Package Size
30's{6's blister (4's - 150mg Nirmatrelvir +2's - 100mg Riotanavir) x5}
Price & Supplier
Price in UAE: AED 4847.00
Dosage Information
Adult Dose
Nirmatrelvir 300 mg (two 150 mg tablets) plus Ritonavir 100 mg (one 100 mg tablet) taken orally twice daily for 5 days.
Pediatric Dose
Not established for patients under 12 years of age or weighing less than 40 kg.
Side Effects
Common side effects include diarrhea, nausea, vomiting, altered taste, and hypertension.
Contraindications & Precautions
Contraindicated in patients with a history of severe allergic reactions to Nirmatrelvir, Ritonavir, or any component of the formulation. Use with caution in patients with liver disease or those taking medications that are contraindicated with Ritonavir.
Important Warnings
Risk of drug interactions due to Ritonavir's effect on CYP450 enzymes; monitor for potential interactions with other medications. Not recommended for use in patients with severe renal impairment (eGFR < 30 mL/min).
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.