About NIROGACESTAT
Class: | Antisense oligonucleotide therapy
Use: | Treatment of patients with amyotrophic lateral sclerosis (ALS) associated with a specific genetic mutation (SOD1-ALS)
Adult dose: | 50 mg administered once daily
Pediatric dose: | Safety and efficacy not established in pediatric populations
Side effects: | Common side effects include injection site reactions, nausea, fatigue, and headache
Contraindications: | Hypersensitivity to the active substance or any of the excipients; caution in
Drug Class
Antisense oligonucleotide therapy
Uses & Indications
Treatment of patients with amyotrophic lateral sclerosis (ALS) associated with a specific genetic mutation (SOD1-ALS)
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light and moisture
Manufacturer & Packaging
Manufacturer: SpringWorks Therapeutics, Inc., United States of America
Package Size
180's
Price & Supplier
Price in UAE: AED 127260.00
Dosage Information
Adult Dose
50 mg administered once daily
Pediatric Dose
Safety and efficacy not established in pediatric populations
Side Effects
Common side effects include injection site reactions, nausea, fatigue, and headache
Contraindications & Precautions
Hypersensitivity to the active substance or any of the excipients; caution in patients with renal impairment
Important Warnings
Risk of serious infections; monitor for signs of respiratory distress; not recommended for use in patients with significant renal impairment or those receiving concurrent nephrotoxic agents
Related Medicines in Same Category
See also: Other Antisense oligonucleotide therapy medicines available in UAE pharmacies
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Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.