About Omacetaxine
Class: | Antineoplastic agent, protein synthesis inhibitor
Use: | Treatment of adult patients with chronic myeloid leukemia (CML) who are resistant to or intolerant of two or more tyrosine kinase inhibitors
Adult dose: | Initial dose of 1.25 mg/m² subcutaneously twice daily for 14 days, followed by a 7-day treatment-free interval; may repeat cycles based on clinical response
Pediatric dose: | Safety and efficacy have not been established in pediatric patients
Side effects: | Common side
Drug Class
Antineoplastic agent, protein synthesis inhibitor
Uses & Indications
Treatment of adult patients with chronic myeloid leukemia (CML) who are resistant to or intolerant of two or more tyrosine kinase inhibitors
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: Teva Pharmaceuticals, U.S.A
Package Size
1 Vial
Price & Supplier
Price in UAE: AED 5893.75
Dosage Information
Adult Dose
Initial dose of 1.25 mg/m² subcutaneously twice daily for 14 days, followed by a 7-day treatment-free interval; may repeat cycles based on clinical response
Pediatric Dose
Safety and efficacy have not been established in pediatric patients
Side Effects
Common side effects include injection site reactions, nausea, diarrhea, fatigue, thrombocytopenia, neutropenia, and anemia
Contraindications & Precautions
Hypersensitivity to omacetaxine or any component of the formulation; caution in patients with a history of bleeding disorders or severe hepatic impairment
Important Warnings
Risk of myelosuppression, including thrombocytopenia, neutropenia, and anemia; monitor blood counts regularly; potential for serious infections; use caution in patients with hepatic impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.